Extended Data Fig. 5: Dependence of axonal propagation speed on eccentricity in human and macaque retinae.
From: Synchronization of visual perception within the human fovea
a, Histograms of normalized action potential speed from three different locations in the human retina (schematic on the left) showing bimodal distributions. Dashed line: fit of Gaussian mixture model with two components; red dots: position of the peaks. Far periphery (i, peaks: 1.04 m s−1 and 1.60 m s−1, N = 238), mid periphery (ii, peaks: 0.84 m s−1 and 1.38 m s−1, N = 68) and center (iii, peaks: 0.57 m s−1 and 0.84 m s−1, N = 264). b, Mean action potential speeds in human retinal explants along the naso-temporal axis by distance from the optic disc; temporal (negative x axis) versus nasal (positive x axis). The numbers indicate the RGC count; shaded region: mean ± s.d. Dashed vertical lines mark optic disc boundaries. c, Histograms of normalized action potential speeds in macaque retina (four explants from the far periphery). S: superior (peaks: 0.92 ms−1 and 1.31 m s−1), N: nasal (0.93 m s−1 and 1.31 m s−1), I: inferior (0.98 m s−1 and 1.40 m s−1), T: temporal (0.92 m s−1 and 1.31 m s−1, N = 280). Dashed line: fit of Gaussian mixture model with two components; red dots: position of the peaks. Illustration in panel c is created with BioRender.com. d, Same as b but for macaque retina.
