Extended Data Fig. 8: Effects of 5-MeO on c-Fos and Npas4 immunofluorescence shown in mouse coronal slices.

Valid clusters from each contrast in Fig. 5 are shown in coronal brain slices overlayed with a wire frame version of the atlas with ABA coloring. Each cluster was randomly colored and labeled with its ID. Clusters shown in Fig. 5c are indicated by lines connecting the ID to the cluster. Major columns correspond to the immunolabel and minor columns represent effect directions. FDR q value thresholds were 0.05 (Npas4) and 0.005 (c-Fos). Voxel coordinates are indicated and can be related to the center of gravity in Table S2. VEH = vehicle; 5-MeO = 5-methoxy-N,N-dimethyltryptamine.