Extended Data Fig. 8: Behavioral analysis in Gria1-3 cKO mice.
a, BMS score in Gria1-3 cKO mice showed a trend towards increased recovery with CX546 treatment compared to vehicle controls. Data are mean ± s.e.m., n = 10 mice in cKO+vehicle, n = 11 in cKO + CX546. Two way ANOVA. b, There was no significant improvement in FLAS testing in cKO mice treated with CX546 compared to vehicle control. Data are mean ± s.e.m., n = 10 mice in cKO+vehicle, n = 11 cKO + CX546. Two tailed Mann Whitney test. c, Catwalk metrics in Gria1-3 cKO mice treated with vehicle or CX546 showed minimal differences. Data are mean ± s.e.m., n = 10 mice in cKO+vehicle, n = 11 in cKO + CX546. Body speed two-tailed t-test, forelimb swing speed two-tailed t-test, hindlimb step cycle two-tailed Mann Whitney test.
