Extended Data Fig. 9: Knockdown of β-arrestin in the CDNs prevents most aspects of satiety without altering baseline motivation. | Nature Neuroscience

Extended Data Fig. 9: Knockdown of β-arrestin in the CDNs prevents most aspects of satiety without altering baseline motivation.

From: Behavioral devaluation by local resistance to dopamine

Extended Data Fig. 9: Knockdown of β-arrestin in the CDNs prevents most aspects of satiety without altering baseline motivation.

(A) Knockdown of β-arrestin (Kurtz) does not change motivational dynamics within a single mating (n = 20-33). (B) Individual traces corresponding to Fig. 5c: dopamine application activates CaMKII in not satiated and satiated animals when Kurtz is knocked down in the CDNs (n = 10 each). (C) Full traces from the data in Fig. 5d (n = 9-10). (D) Knockdown of Kurtz does not block the satiety-induced potentiation of the termination response to optogenetic activation of the CDNs (n = 26-28).

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