Extended Data Fig. 4: CFA inactivation effects across muscle activity state space. | Nature Neuroscience

Extended Data Fig. 4: CFA inactivation effects across muscle activity state space.

From: Selective direct influence of motor cortex on limb muscle activity during naturalistic climbing in mice

Extended Data Fig. 4: CFA inactivation effects across muscle activity state space.The alternative text for this image may have been generated using AI.

a–c, Inactivation effect maps and corresponding p-value maps for each of the four muscles in three additional mice. Q-values (gray overlay) reflect the expected rate of false discovery below the corresponding p-value46. For the effect sizes, color scale max and min reflect the maximum and minimum effect sizes across all four muscles. Thus, the maps for muscles with smaller effect sizes do not use the full range of colors. d, Alternate versions of the inactivation effect maps shown in Fig. 2j in which the color scale applies separately to each map, so the same colors correspond to the different maximum and minimum values on each map. e, For three additional mice, maps in which each grid point is colored by the mean distance (in 80D) between all pairs of embedded states, with each distance weighted by a Gaussian function of the pair’s mean distance from the grid point on the 2D map. f–i, Same as c, but following calculation with slightly different parameters (red text).

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