Extended Data Fig. 5: CFA selectively excites physiological flexors. | Nature Neuroscience

Extended Data Fig. 5: CFA selectively excites physiological flexors.

From: Selective direct influence of motor cortex on limb muscle activity during naturalistic climbing in mice

Extended Data Fig. 5

a, P-value distributions for inactivation effects on each muscle when calculated by comparing control trials to a separate set of control trials, for all grid points across all 8 mice. Error bars indicate the sem. b, c, For two additional mice (b shows mouse DC50, c shows mouse DC44), scatterplots of inactivation effect size versus muscle activity at trial onset (averaged from -40 to +10 ms relative to onset). Each point reflects a different grid point. R2 is for a linear fit (red). d, e Same as Fig. 3f (d) and 3g (e), except only including grid points where effect size was significantly different from zero. Note that the y-axis scale in e differs from that in Fig. 3g. As was true when using all effect sizes, residuals from linear fits for these subsets were significantly different from uniform (p < 0.004 for all mice, two-sided K-S test).

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