Fig. 2: Brain shape reflects infant maturity beyond differences in brain size.
From: Fractal analysis of brain shape formation predicts age and genetic similarity in human newborns
a, Cross-sectional correlations between infant age at scan and FD as a measure of brain shape (left) and volume (Vol) as a measure of brain size (right; two-tailed product−moment correlation tests). Correlation coefficients were Fisher z-transformed and thresholded to P < 0.05 after false discovery rate (FDR) adjustment. b, Region-wise comparison of age effects (two-tailed Williams’ test of absolute effect size; example regions: parietal GM left, PFDR = 2.3 × 10−10; parietal WM left, PFDR = 2.7 × 10−5; thalamus left: PFDR = 0.10). For color-coded regions, the null hypothesis that FD and Vol are equally strongly correlated with age was rejected at P < 0.05 after FDR adjustment. Higher age correlations for brain shape are shown on the left; higher age correlations for brain size are shown on the right. Note that, in some regions (for example, the thalamus), infant age was reflected equally strongly by both measures. NS, not significant.
