Supplementary Figure 6: Analysis of altered chromatin signals and consistency of results across independent cell-culture replicates.
From: Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers
All fold changes below refer to changes that arise in G784E/WT mESCs compared to WT/WT mESCs. (a) MA plot of fold change of ATAC read density at individual sites across the genome. (b) Reproducibility of ATAC changes across independent cell-culture replicates. (c) MA plot of fold change of H3K4me1 read density at individual sites across the genome. (d) Reproducibility of H3K4me1 changes across independent cell-culture replicates. (e) MA plot of fold change of H3K27ac read density at individual sites across the genome. (f) Reproducibility of H3K27ac changes across independent cell-culture replicates. (g) MA plot of fold change of RNAP2 read density at individual sites across the genome. (h) Reproducibility of RNAP2 changes across independent cell-culture replicates.
