Supplementary Figure 7: Examples of enhancer changes across the genome.
From: Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers
(a) Example of enhancer accessibility loss coinciding with H3K27ac loss but not H3K4me1 loss on chromosome 8. (b) Example of enhancer accessibility loss coinciding with H3K27ac loss but not H3K4me1 loss on chromosome 10. (c) Example of enhancer accessibility loss coinciding with H3K27ac loss but not H3K4me1 loss on chromosome 2. These changes are representative of the dominant-negative effects of SMARCA4 mutations on the enhancer landscape.
