Supplementary Figure 9: SMARCA2 (BRM) is repressed in wild-type and mutant SMARCA4 mESCs. | Nature Structural & Molecular Biology

Supplementary Figure 9: SMARCA2 (BRM) is repressed in wild-type and mutant SMARCA4 mESCs.

From: Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers

Supplementary Figure 9: SMARCA2 (BRM) is repressed in wild-type and mutant SMARCA4 mESCs.

Expression of SMARCA2 compared to other genes in mutant and wild-type mESCs. Little to no SMARCA2 is expressed in mESCs, either in wild-type or mutant cells. Counting of transcripts reveals that SMARCA2 is expressed at less than 1% compared to SMARCA4, hence confounding effects due to SMARCA2 expression can be excluded. Plotted values are mean normalized expression counts (a.u.), error bars are 95% confidence intervals from independent cell-culture replicates (n=2).

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