Supplementary Figure 2: Cryo-EM density.
From: Cryo-EM structure of the human neutral amino acid transporter ASCT2
Sections of the cryo-EM density of the ASCT2 map superimposed on the respective refined models. Models are shown as sticks and structural elements are labelled. Transmembrane helices of the transport domain are coloured in blue, of the scaffold domain in yellow and the loop between TM4b and TM4c is shown in red. Densities sharpened with a b-factor of −225 Å2 were plotted at 5σ, except for the loop between TM4b-TM4c, which was contoured at 3σ.
