Supplementary Figure 3: Superposition of subunits of the yeast supercomplex (III2IV) with the corresponding proteins from cow (Bos taurus) and pig (Sus scrofa).
From: Cryo-EM structure of the yeast respiratory supercomplex
a, Superposition of yeast Cor1 (PDB 3CX5) with Cor1 from the yeast supercomplex, III2IV, showing comparison between Cor1 subunit bound to Cox5a and the unoccupied side of CIII. b, Superposition of yeast Rip1 (PDB 3CX5) and the S. scrofa Rip1, in the loading state (PDB 5GUP) with Rip1 from the yeast supercomplex, (III2IV) show significant movement of the head domain and the hinge region residues: 90–93 compared to the yeast crystal structure but similar to the Rip1 in the loading state from the mammalian respirasomes. c, Superposition of the cytochrome c oxidase from the yeast supercomplex, III2IV, with bovine cytochrome c oxidase (PDB 1V54). d, Superposition of Cox4 (PDB 1V54) with Cox5a from the yeast supercomplex, III2IV.
