Supplementary Figure 6: Structure comparison of ribosome-bound Xrn1.

Comparison of the S.c. ribosome–Xrn1 complex (a) with unbound D. melanogaster Xrn1 structure superimposed on the S.c. ribosome (b). Three loops engaged in interactions with ribosomal components are depicted (L1 = 119–129, L2 = 46–56, L3 = 227–244) as well as the potential clash of the superimposed Winged helix domain with ribosomal protein eS28.