Supplementary Fig. 9: Characterizing the high-confidence m5C sites in human and mouse.
From: Genome-wide identification of mRNA 5-methylcytosine in mammals
(a) The number of m5C sites identified in human and mouse tissues or cells. The number of mapped reads in each library was shown as dots. (b) Genic positions of m5C sites. 5′ UTR, CDS and 3′ UTR of protein-coding genes were shown. ncRNA, Non-coding transcripts. (c) The distribution of m5C sites across the transcripts. Sites identified in all samples were first combined. Next, each m5C site was assigned to the longest isoform of the corresponding gene. The number of bins was determined based on relative lengths between 5’UTR, CDS and 3’UTR (human, 10, 50 and 40 bins; mouse, 10, 60 and 50 bins). The red curve was fitted with polyfit. (d) The cluster degree of m5C sites in human and mouse.
