Supplementary Fig. 10: The profiles of mRNA m5C in different tissues.
From: Genome-wide identification of mRNA 5-methylcytosine in mammals
(a) The number of sites that are shared between tissues in human and mouse. (b) Heatmap of normalized m5C levels in human and mouse. For each species, only sites with methylation levels ≥ 10% in at least one sample were selected for analysis. The methylation levels are normalized across samples for each site. NA was treated as zero. (c) Gene Ontology (GO) terms enriched in m5C containing genes in mice muscle and heart. Sites with methylation level > 20% were selected. GO terms with a BH corrected p value < 0.01, enrichment score > 1.5 and gene counts > 10 were shown. Go term analysis were performed using David and biological process, molecular function and cellular component were selected.
