Supplementary Figure 1: CryoEM analysis of apo and holo HCoV-OC43 S glycoprotein.
From: Structural basis for human coronavirus attachment to sialic acid receptors
a, c, Representative electron micrographs (defocus: 1.4 μm and 1.2 µm) and class averages of apo (a) and holo (c) HCoV-OC43 S trimer embedded in vitreous ice. Scale bars: 100 nm (micrograph) and 200 nm Å (class averages). b, d Gold-standard (blue) and model/map (red) Fourier shell correlation curves. The resolution was determined to 2.9 Å and 2.8 Å for the apo and holo HCoV-OC43 S glycoprotein maps, respectively. The 0.143 and 0.5 cut-off values are indicated by horizontal dashed lines.
