Supplementary Figure 2: Experimental phasing and structure determination of dilazep-bound hENT1cryst. | Nature Structural & Molecular Biology

Supplementary Figure 2: Experimental phasing and structure determination of dilazep-bound hENT1cryst.

From: Structures of human ENT1 in complex with adenosine reuptake inhibitors

Supplementary Figure 2: Experimental phasing and structure determination of dilazep-bound hENT1cryst.The alternative text for this image may have been generated using AI.

a, Stereo view of the final model in the initial density modified SIRAS map (1σ) to 3.5 Å. b, Stereo view of the final model in 2Fo-Fc composite omit calculated map (1σ), to 2.3 Å. c, Protein cross-section view of dilazep binding site, final model in 2Fo-Fc composite omit calculated map (1σ), to 2.3 Å. d, Fo-Fc simulated annealing omit map (3σ) to 2.3 Å, calculated using a starting temperature of 2,500K.

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