Supplementary Figure 2: Alignment of Titan Krios microscope.
From: Cryo-EM structures of four polymorphic TDP-43 amyloid cores

a, (Left) Computed diffraction pattern from a micrograph containing crystalline ice with reflections visible to 1.95 Å demonstrating proper alignment of the microscope. (Right) Representative CTFFIND4 diagnostic image. b, Representative estimation and correction of anisotropic magnification distortion.