Supplementary Figure 4: Density maps of TDP-43 fibril structures. | Nature Structural & Molecular Biology

Supplementary Figure 4: Density maps of TDP-43 fibril structures.

From: Cryo-EM structures of four polymorphic TDP-43 amyloid cores

Supplementary Figure 4

Different views of the four structures reported in this study, with 5 layers of each structure shown. Density maps are shown in colored mesh and atomic model are shown in grey cartoons. Top-views demonstrate clear separation of beta-strands while tilted views demonstrate clear separation of the beta-sheets in the z-direction.

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