Extended Data Fig. 6: Superposition of S6 of TAX-4 orthologs.
From: Mechanism of ligand activation of a eukaryotic cyclic nucleotide−gated channel
a,b, Superposition of S6 (viewed from the extracellular side) of cGMP-bound (open state) TAX-4, apo (closed state) TAX-4, apo SthK (PDB ID: 6CJQ) and apo LliK (PDB ID: 5V4S), showing the presence of a hydrophobic cavity gate in all the apo structures.
