Extended Data Fig. 2: Overview of single-particle cryo-EM for mTRPV3-ΔN in a nanodisc.
From: The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism
a, Cryo-EM micrograph of mTRPV3-ΔN in a nanodisc, with example particles circled in red. b, Reference-free 2D class images of mTRPV3-ΔN in a nanodisc. c, 3D class averages of mTRPV3-ΔN in a nanodisc. d, Refined density, at 3.31 Å resolution (FSC = 0.143). e, FSC curves of the map of TRPV3 in a nanodisc. The horizontal dashed line indicated FSC = 0.143. f, Euler angular distribution for particles used in the final map of TRPV3 in a nanodisc.
