Extended Data Fig. 2: β2 subunit, if intact, would clash with the bound Nef. | Nature Structural & Molecular Biology

Extended Data Fig. 2: β2 subunit, if intact, would clash with the bound Nef.

From: Structural basis of CD4 downregulation by HIV-1 Nef

Extended Data Fig. 2

Overlay of the intact β2 subunit (dark red, PDB 2XA7) with β2 in the current structure (green) indicates that clashing would take place between Nef and N-terminus of the intact β2, specifically residues Asn10, Lys11, Lys12, and Gly13 (spheres).

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