Extended Data Fig. 4: Binding of Nef N-terminal helix to the Nef core is incompatible with CD4 downregulation. | Nature Structural & Molecular Biology

Extended Data Fig. 4: Binding of Nef N-terminal helix to the Nef core is incompatible with CD4 downregulation.

From: Structural basis of CD4 downregulation by HIV-1 Nef

Extended Data Fig. 4

N-terminal helix of Nef (8-23) is modeled into the current structure. Red dotted line represents the would-be distance between residues 23 and 34, which cannot be covered by ten residues (Nef 24-33).

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