Extended Data Fig. 7: MER57E3 is enriched in KRAB-ZF-encoding genes that have rapidly evolved in primates or humans.
From: Endogenous retroviruses drive species-specific germline transcriptomes in mammals
a, Representative track views show H3K27ac ChIP-seq enrichment for whole, adult human testis tissue and RNA-seq signal in human KIT+ and PS. Red highlights indicate enhancer-like MER57E3s that overlap high levels of H3K27ac deposition. b, Pie charts indicate the genomic distribution of enhancer-like MER57E3 loci in the human genome (hg38). Most enhancer-like MER57E3s are located within the first intronic regions of KRAB-ZF-encoding genes.
