Fig. 2: Register shift in the C terminus of RNA polymerase.

a, Overview with missing loop shown as a dashed line (PDB 7BV2); map at 2.4σ. Right, details of the C-terminal helix at 5σ. b, Lower resolution map and model (PDB 6NUS). Judging the side chain fit is difficult. c, Higher resolution map and model (PDB 7BV2) as deposited; the side chain fit is suboptimal due to the register error. d, Amended model for PDB 7BV2; the side chains now fit the density. The register shift is indicated by the labelled Tyr915. Picture: CSTF/insidecorona.net.