Fig. 1: Cryo-EM structures of S-UK.
From: Effect of SARS-CoV-2 B.1.1.7 mutations on spike protein structure and function
a, Domain structure of S-UK with the nine B.1.1.7 mutations indicated. The D614G mutation common to most emerging SARS-CoV-2 strains is highlighted in blue. b, Four different classes of conformations of S-UK derived from cryo-EM 3DVA. The relative populations of the individual classes are indicated in the pie chart and the number of RBD in the upward conformation (RBD-up) of each class is indicated below, along with the nominal resolution in parentheses. The positions of the RBD-up are indicated by red asterisks. Source data for b are available online (see the source data for Extended Data Fig. 1).
