Extended Data Fig. 4: Correlation analysis of Hi-C and simulated contact maps for chromosome 22.
From: Three-dimensional genome organization via triplex-forming RNAs
(a) Distribution of the diagonal cross-correlation coefficients (dCCC) (Methods) in chromosome 22 of the contact maps derived from the ensemble of 3D models with Hi-C. Box boundaries represent 1st and 3rd quartiles, middle line represents median, and whiskers extend to 1.5 times the interquartile range. The statistical significance of the difference between each pair of dCCC distributions has been assessed with the two-sided Mann-Whitney rank test using python default parameters. The p-values are < 10−3 unless reported; n = 1026 equal to the number of beads in chromosome 22.
