Extended Data Fig. 4: Fitting of the atomic model with the EM density in selected regions of the Rad24-RFC–9-1-1 clamp–DNA complex 3D maps.
From: DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp
The central panel shows the segmented 3D map in 90% transparent surface view, except for the nine selected regions shown in solid surface. The nine selected regions – one from each component of the ternary complex – are shown in peripheral panels, with the atomic model in cartoon and residues in sticks, and with the EM density shown in wire meshes. For a fuller representation, the selected upper regions (Rad24-RFC–DNA) used the EM map in the open state, and the selected lower 9-1-1 clamp regions are from the EM map in the closed state.
