Fig. 3: CENP-N folds CENP-A chromatin into a regular fiber.
From: CENP-N promotes the compaction of centromeric chromatin
a, A nucleosomal array consisting of six CENP-A nucleosomes with CENP-N was fit into the density map. Dashed circles indicate weak densities representing more disordered nucleosomes at both ends. b, CENP-N interacts with nucleosomal DNA of a neighboring nucleosome (CENP-N α6 binds between SHL6 and 7 (left)). This is in contrast to mononucleosome stacks, where CENP-N α6 binds between SHL4 to 5 (right). c, The relative arrangement of nucleosomes in the arrays was expressed in analogy to the arrangement of DNA bases in a double helix. Parameters for CENP-N fibers (left, EMD-26333) and H1 fibers32 are shown. The vectors in the middle show the parameters of the analysis (in red for CENP-A arrays, and cyan for H1 arrays).
