Extended Data Fig. 5: Overview Hi-C analyses of different genotypes.
From: The cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism
(a) Hi-C contact matrices for G1 cells of the indicated genotypes. A locus at chromosome 4 is shown at 10-kb resolution. Matrices were normalized to 100 million contacts per sample. (b) Hi-C contact matrices for G1 cells of the indicated genotypes. A locus at chromosome 4 is shown at 10-kb resolution. Matrices were normalized to 100 million contacts per sample. These Hi-C libraries were less deeply sequenced than the Hi-C libraries presented in (a). (c) Aggregate peak analysis (APA) for primary loops using the same scale for all genotypes. The bottom right value depicts the APA score. (d) APA for extended loops using the same scale for all genotypes. The bottom right value depicts the APA score.
