Extended Data Fig. 3: Receptor-G protein interface comparison between dimAPJRcmpd644-Gi and monAPJRcmpd644-Gi complexes. | Nature Structural & Molecular Biology

Extended Data Fig. 3: Receptor-G protein interface comparison between dimAPJRcmpd644-Gi and monAPJRcmpd644-Gi complexes.

From: Structural insight into apelin receptor-G protein stoichiometry

Extended Data Fig. 3

a–c, Interactions between dimeric APJR ProtA (rainbow colored surface) and Gαi protein (blue cartoon). Interface residues are shown as sticks. d–f, Interactions between monomeric APJR (rainbow colored surface) and Gαi protein (yellow cartoon). Interface residues are shown as sticks. g, Sequence alignment of APJR-Gαi interface (residues on the receptor within 5 Å to the G protein) with other class A GPCR-Gi structures using Jalview v2.11.1.4.

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