Extended Data Fig. 6: ITC analysis of TEL-MTase and MTase domain with SAM, SAH and SFG.
From: High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development
ITC titration data for SAM (left), SAH (middle) and SFG (right) with the TEL-MTase fusion (a) and the MTase domain alone (b). The equilibrium dissociation constants (KD) were derived from the resulting binding isotherms.
