Extended Data Fig. 7: Schematic depiction of multi-state design framework and characterization pipeline. | Nature Structural & Molecular Biology

Extended Data Fig. 7: Schematic depiction of multi-state design framework and characterization pipeline.

From: Computational design of constitutively active cGAS

Extended Data Fig. 7: Schematic depiction of multi-state design framework and characterization pipeline.The alternative text for this image may have been generated using AI.

The key steps of the design and characterization pipeline are depicted schematically. The steps at which each CA-cGAS variant was discovered are indicated.

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