Extended Data Fig. 5: IP6 binding to immature hexamers.
From: HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly
Model of IP6 binding to immature HIV-1 hexamers. IP6 (orange & yellow sticks) is coordinated by two rings of lysines at position K227 (yellow sticks) and K158 (green sticks). The axial phosphate in the inositol ring is labeled (2’PO4) along with the six helix bundle (6HB) that is formed by the SP1 domain in Gag. Based on PDB 6BHR.
