Extended Data Fig. 3: A putative CHK-2 target site in the FAT domain of ATL-1 does not promote its kinase activity.
From: ATM signaling modulates cohesin behavior in meiotic prophase and proliferating cells
a, Alignment of residues at the C-terminus of the FAT domains of C. elegans ATM-1 and ATL-1. CHK-2 consensus motifs are highlighted. The conserved serines and arginines at the -3 position are marked by asterisks. b, Viability of embryos and frequency of male self-progeny from hermaphrodites homozygous for the indicated alleles. Null alleles of both atm-1 (atm-1(gk186)) and atl-1 (atl-1(tm853)) were assayed for comparison. The number of eggs scored for each allele is shown in parentheses. Data for graphs in b are available as source data.
