Extended Data Fig. 7: Cryo-EM analysis of the Mdm2-5S RNP complex.
From: Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2–p53 pathways
a,b, Representative micrograph of the Mdm2-5S RNP assembly low-pass filtered to 20 Å, displayed with inverted contrast (out of 2454 micrographs used for processing) (a) and selected 2D classification averages (b). Scale bar: 50 nm. c, Cryo-EM processing scheme of the Mdm2-5S RNP. The overall resolution of the final 3D reconstruction was 4.1 Å. d, FSC curves of the final 3D reconstructions showing masked and unmasked FSC curves. e, Model-to-map FSC curves. f, Final 3D reconstruction filtered and colored according to local resolution.
