Extended Data Fig. 6: Extracellular gate H-bond network comparison.
From: Cryo-EM structure of GABA transporter 1 reveals substrate recognition and transport mechanism
The figure displays the comparison of rGAT1 and hGAT1 with a Cα rmsd of 0.9 Å. The interactions of a, rGAT1 extracellular gate compared with b, hGAT1 (PDB id. 7SK2, Cα rmsd – 0.9 Å), c, hGlyT1 (PDB id. 6ZBV, Cα rmsd – 1.0 Å), d, hSERT (PDB id. 6DZZ, Cα rmsd – 1.3 Å) and e, LeuT (PDB id. 3TT3, Cα rmsd – 1.7 Å) extracellular gate H-bond network.
