Extended Data Fig. 3: Cryo-EM data validation. | Nature Structural & Molecular Biology

Extended Data Fig. 3: Cryo-EM data validation.

From: Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2

Extended Data Fig. 3

a, Final cryo-EM reconstructions. b, Fourier-shell correlation for the final reconstruction, generated from cryoSPARC. c, projection orientation distribution map for the final reconstruction, generated from cryoSPARC. d, Map-to-model correlation plots. e, Local Resolution plots. f, cryo-EM maps for secondary structure segments. From left to right are cryo-EM data validations for apo-OCT1CS, DPH-OCT1CS, VPM-OCT1CS, and MPP+-OCT2CS datasets, respectively.

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