Extended Data Fig. 4: Tissue-specific viral burdens and hACE2 expression in K18-hACE2 mice at 1 and 3 days post infection (dpi).
From: Structural and functional characteristics of the SARS-CoV-2 Omicron subvariant BA.2 spike protein
Mice were intranasally inoculated with 100 TCID50/50 μl/mouse of G614 (B.1), Delta (B.1617.2), Omicron-BA.1 or BA.2. The viral RNA copies (a) or hACE2 expression (b) in various tissue homogenates were measured by RT-qPCR. Data are expressed as geometric means (bars) with geometric standard deviation (error bars). Individual results of infected mice (n = 4 mice/time point/group) and uninfected naïve mice (n = 5) are shown.
