Fig. 3: Recognition of probenecid.
From: Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1
a, Cryo-EM density for probenecid in site 3 (purple and threshold 0.237). b, Schematic of probenecid interactions. c, Mutational analysis of probenecid binding site. IC50 values are the mean of three independent experiments; errors shown are s.d. Inset shows the sequence alignment of OATs with respect to the conservation of Asn35.
