Extended Data Fig. 1: Cryo-EM data processing workflow.
From: Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge
a, Processing workflow for Chi. Particles belonging to teal maps were carried into the next round of processing. b, Cryo-EM map of Chi (dyneinE2488Q-Lis1)2 colored by local resolution. c, Fourier shell correlation (FSC) plot for Chi. d, Symmetry expansion followed by local refinement map of dyneinE2488Q-(Lis1)2. e, Local refinement of symmetry expanded dyneinE2488Q-(Lis1)2 colored by local resolution. f, FSC plot for local refinement map.
