Fig. 6: Schematic model of NuRD function.
From: Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD
Left, a molecular level view of how assembly of the NuRD complex affects chromatin remodeling18. Right, a chromatin level view of how assembly of the NuRD complex increases the volume explored by an enhancer while at the same time reducing its likelihood of entering the fast F2 state in which the movement of decondensed chromatin might reset enhancer–promoter proximity.
