Extended Data Fig. 1: Characterization of ΔEMC cells.
From: EMC rectifies the topology of multipass membrane proteins
Serial dilutions of total microsomes from WT or ΔEMC cells were analyzed by SDS-PAGE and immunoblotting for the indicated ER-resident proteins. These data complement earlier analysis for additional ER proteins (including Sec62, Sec63, TRAM, TRAPα, the 12 kD subunit of the signal peptidase complex, and other EMC subunits) using the same parental and ΔEMC cells4.
