Extended Data Fig. 4: RT-qPCR analysis of GV oocytes with indicated genotypes.
From: Auto-suppression of Tet dioxygenases protects the mouse oocyte genome from oxidative demethylation
a, RT-qPCR analysis of LTR-ERV subfamilies and representative non-LTR TEs in oocytes with the indicated genotypes. b, Pie chart illustrating the proportion of upregulated genes with an adjacent ERVK in 500 kb. c, RT-qPCR analysis of 5 representative genes upregulated in correlation with ERVK derepression in oocytes within the indicated groups. a, c, 200 oocytes were pooled together for each sample. The expression levels were normalized to 18s rRNA, and then compared to WT, which were set to 1.0. Mean and s.e.m. were determined from five biological replicates. Statistical significance (indicated P value) was analyzed using an unpaired two-tailed Student’s t-test.
