Extended Data Fig. 2: Cryo-EM Data Analysis for the GR:Hsp90:FKBP52 Complex.
From: Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor
a, Cryo-EM data processing procedure for the GR:Hsp90:FKBP52 complex performed in RELION and CryoSparc. Gold-standard Fourier shell correlation (GSFSC) curves of the final 3D reconstructions, including the focused maps and the consensus map, are shown (bottom). The blue lines intercept the y-axis at an FSC value of 0.143. Angular distribution of particles and local resolution are shown for the consensus map (bottom, middle). b, Map-to-model FSC curves between the GR:Hsp90:FKBP52 atomic model and the consensus GR:Hsp90:FKBP52 map, along with different views of the model within the map. The black dotted line intercepts the y-axis at an FSC value of 0.5.
