Extended Data Fig. 10: Structural comparison of JARID2, AEBP2, and SSX1 bound to the H2AK119Ub nucleosome. | Nature Structural & Molecular Biology

Extended Data Fig. 10: Structural comparison of JARID2, AEBP2, and SSX1 bound to the H2AK119Ub nucleosome.

From: Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes

Extended Data Fig. 10

a. Close-up view of the contact between JARID2 and Ub. Ub is shown in a crimson surface. JARID2 and nucleosomes are shown in cartoon. b. Close-up view of the contact between AEBP2 and Ub. Ub is shown in media spring orange surface. c. Close-up view of the contact between SSX1 and H3-UbH2AK119 basic groove. Ub is shown in yellow surface. d. Structural comparison of JARID2, SSX1, AEBP2 bound to the H2AK119Ub nucleosome. Histone octamer is shown in light grey surface. e. Comparison of the position of Ub in the structure of AEBP2 bound to H2AK119Ub nucleosomes and the structure of JARID2 bound to H2AK119Ub nucleosomes. f. Comparison of the position of Ub in the structure of AEBP2 bound to H2AK119Ub nucleosomes and the structure of SSX1 bound to H2AK119Ub nucleosomes.

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