Extended Data Fig. 9: Comparison of JTE-607 treatment with Ube3d knockdown. | Nature Structural & Molecular Biology

Extended Data Fig. 9: Comparison of JTE-607 treatment with Ube3d knockdown.

From: The anticancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3′ processing machinery

Extended Data Fig. 9

(a) Poly(A) site usage index (PDUI) in control and Ube3d knockdown cells. Blue dot: genes with significant 3′ UTR lengthening; Red dots: genes with significant 3′ UTR shortening. (b) A Venn diagram comparing the genes with significant APA changes in Ube3d knockdown and JTE-607-treated cells.

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