Extended Data Fig. 5: Docking of a 14-carbon acyl group into the catalytic sites of Erf2 and DHHC9. | Nature Structural & Molecular Biology

Extended Data Fig. 5: Docking of a 14-carbon acyl group into the catalytic sites of Erf2 and DHHC9.

From: Regulation of RAS palmitoyltransferases by accessory proteins and palmitoylation

Extended Data Fig. 5: Docking of a 14-carbon acyl group into the catalytic sites of Erf2 and DHHC9.

a,d, The solvent-accessible surface of the Erf2-Erf4 complex (a) and that of the DHHC9-GCP16 complex (d) were generated in PyMOL. The surface transparency was set to 20% to show the acyl groups behind the surfaces. The 14-carbon acyl group in each structure is shown as sticks and colored magenta. b,c, Docking of a 14-carbon acyl group (b) or a 16-carbon acyl group (c) into the cryo-EM map of the Erf2-Erf4 complex. e,f, Docking of a 14-carbon acyl group (e) or a 16-carbon acyl group (f) into the cryo-EM map of the DHHC9-GCP16 complex.

Back to article page