Extended Data Fig. 5: AlphaFold Multimer prediction of CCDC22-CCDC93 binding to Retriever.
From: Structural organization of the retriever–CCC endosomal recycling complex
(a & d) Overlay of all 25 AlphaFold Multimer models of Retriever alone (A) or CCDC22-CCDC93-Retriever (D) with the cryo-EM model of Retriever. AFM models of Retriever are grey. (b & e) Representative AFM models colored using pLDDT scores. High scores indicate high reliability in local structure prediction. (c & f) PAE score matrix of the AFM model shown in (B & E). Low scores (deep color) indicate high reliability in the relative position in the 3D space. Boundaries of protein sequences and important structure regions are indicated.
