Extended Data Fig. 8: Pairwise sequence alignments of human and mouse IL-12A, IL-23A and IL-12B.
From: Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23
Sequence alignments are shown between human and mouse orthologs of IL-12A (a), IL23A (b) and IL-12B (c). Secretion signals are indicated with a black line, and secondary structure elements are indicated with helices and arrows for α-helices and β-strands respectively. Residues involved in specific interaction interfaces are annotated using colored dots, and N-linked glycosylation sites are annotated using a star. Pairwise alignments were performed using MAFFT62, and ESPript63 was used for display.
